Sentence examples for respiration defect from inspiring English sources

This decreased mitochondrial volume together with impaired ETC gene expression may explain the mitochondrial respiration defect found only in muscle strips and not in isolated mitochondria [20].

POLGdn can effectively abolish mtDNA replication leading to respiration defect.

Mice fed with regular chow diet and injected with streptozotocin developed cardiac dysfunction without mitochondrial respiration defect.

Gautier et al (2008) proposed that altered mitochondrial dynamics could cause a more general respiration defect, however no evidence was provided.

These data together suggest that the AMPK-mTOR-p70S6K axis play a significant role in maintaining mitochondrial respiration in breast cancer cells, and that its loss in TNBC cells led to respiration defect.

However, we show here that using the variations of the PoP of protons in the intermembrane space of mitochondria is indeed a very good is-marker of respiration defect.

Analysis of cybrids harboring homoplasmic m.3243A>G mutation revealed that the level of aminoacylated tRNALeu UUR) was reduced 70%75%%, which is mainly due to a shortage of tRNALeu UUR), leading to the reduced rate of mitochondrial protein synthesis and respiration defects (Picard et al., 2014).

Taken together, mitochondrial abundance in the larval fat body is reduced under low-yeast food conditions, leading to respiration defects.

In contrast, this was significantly reduced to 2.3-fold when fat bodies were dissected from low-yeast fed larvae, demonstrating respiration defects under these conditions (Fig. 1D).

To test whether reduced expression of OXPHOS genes could explain the respiration defects, we used quantitative PCR (qPCR) to measured mRNA levels from dissected fat bodies.

This results in the inability to produce ubiqinone and menaquinone causing cellular respiration defects [ 100], as well as defects in the cell envelope [ 101].