The attenuation correction was also performed according to the manufacturer's formula, reported, and validated in [13], see Eq. 9, with μ m, μ w, μ a, and μ b the attenuation coefficients of respectively material, water, air, and bone, E the energy of the gamma photons in keV, and Eeff the mean energy of the CT beam.
For OPSCC and OSCC, respectively, material from biopsies and resection specimen was used.
The average areas under the curve (AUC) as measure of prediction accuracy for OG and TSG classifications were 84.21% and 92.17%, respectively (Materials and Methods).
Genes assigned in the LCA to Modules 1 and 5 tend to persist in those modules (Module Stability 94% ± 0.5%and84%4% ± 1.2%, respectively, 'Materials and methods').
Equivalent figures for indels were in keeping with the increased difficulty of scoring these variants from low-pass sequencing data at 84 and 20.7%, respectively (Materials and Methods; Supplementary Material, Fig. S3 and Tables S4 7).
Solid lines represent models of Δ x based on Equation 3 for SSB wrapping N w = 65, 56, 35, and ∼17 nt (purple, blue, green, and red, respectively; 'Materials and methods').
To test this possibility, we performed RNA-seq and quantified changes in gene expression as well as AS in HEK293 cells upon RBM10 knockdown (KD) or overexpression (OE) respectively (Materials and Methods Section).
Module 1 and 5 are the least dynamic as reflected by the average proportion of genes that join (11% ± 1.6% and 17% ± 1.7%, respectively) or leave each module (6% ± 0.4% and 16% ± 1%, respectively) between each pair of ancestor and child species in the phylogeny (Module Expansion Index and Module Contraction Index, respectively, 'Materials and methods'; Figure 5D,E).
sinensis (the Chinese softshell turtle), respectively (supplementary material S1, Supplementary Material online).
The Mendelian discordance rates (Materials and Methods) were 1.04 and 1.18% for CEU and YRI, respectively (Supplementary Material, Table S4).
In this view, two series of test cases, respectively at material point scale and at drift excavation scale are defined.
