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Before data entry, all the trade names were converted into generic names using PharmaGuide[9], and all psychopharmacological medications were coded into different classes according to their respective modes of action like anti-depressants, anxiolytics, etc. and their subtypes.
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A principle challenge faced by the information gleaned from phenotypic screening is that many of the assessed compounds remain orphan ligands, as the respective mode-of-action (MOA) remains undetermined in the first instance [1].
However, several modes of action as well as multiple sites of action have been proposed.[3].
The chapter is structured by the respective biochemical modes of actions of the different substance classes discussed.
based on this pesticidal mode-of-action classification.
Subsequently, mode-of-action and pharmacokinetic information were incorporated.
Mode-of-action models strengthen science in two important ways.
Hence, the prediction of mixture toxicity by CA was generally in good agreement with the observed mixture toxicity particularly when the supposedly more sensitive organisms for the respective pesticidal mode of action was assessed, i.e., algae and Lemna as primary producers in the case of herbicides.
Dexrazoxane has several biological modes of action.
Figure 11 shows images of the two models after testing, verifying the respective mode of response.
We showed that the gene signature data reflected the modes of action of the respective agents.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com