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Cuba's domestic oil and gas resources are substantial.
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The potential for technology diffusion to emerging economies with limited financial resources is substantial.
When disease burdens are large and the call upon resources is substantial, estimates need to be as accurate as possible.
The framework can be used to apply exergy-based indicators for pinpointing the hotspots in food production chains where the irreversible consumption of natural resources is substantial, and for comparing the resource use efficiency of different system designs and configurations.
Use of acute hospital resources was substantial, with heart failure patients occupying almost 200,000 bed-days per year in NSW over the five year study period.
Use of acute hospital resources was substantial, with the patients occupying almost 200,000 bed-days per year in NSW over the five year study period.
Most infections resolve with minimal use of health care resources; however, episodes of severe or recurrent infection may require hospitalization or surgery, and the resultant burden on resources is substantial (Black et al. 2010).
Further, their control of resources is substantial: beyond the patent to the ABCC6 mutations causing the disease, PXE International has built and maintained an important biobank of patient samples and data, and they use these to attract researchers, enforce cooperative relations among them, and steer the course of their work.
When preparing donated primary human fetal tissue for cell transplantation into a recipient PD patient, loss of cells – already a scarce resource – is substantial throughout the procedure from harvest to grafting.
Initial financial and human resources investments are substantial.
Despite this small scale, national resource gaps are substantial if the same standard of clinical care is maintained when fewer cases arise.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com