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In this Resource article, we have built a structure model of the human sodium channel Nav1.7 based on the Cav1.1 cryo-EM structure (PDB code: 5GJV).
In this Resource article, we summarized all the reported disease-related mutations in human Nav channels, generated a homologous model of human Nav1.7, and structurally mapped disease-associated mutations.
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We are delighted to present an issue packed with reviews, research and resource articles from researchers at the cutting-edge of their respective disease area of interest.
Now expanding to address all areas of the plant sciences as an independent journal, APPS is positioned to cover a wide variety of research needs by publishing novel protocols and primers, software notes, reviews, and application and genomic resource articles.
Therefore we would like to ask you to reconsider our submission as a Tools and resources article.
Your Tools and Resources article has been favorably evaluated by John Kuriyan (Senior editor), a Reviewing editor, and three reviewers.
Your Tools and resources article has been favorably evaluated by Fiona Watt (Senior editor), Duncan Odom (Reviewing editor), and two anonymous reviewers.
In addition, "access to genetic resources shall be subject to prior informed consent of the Contracting Party providing such resources" (article 15.5).
Reviewer 2: The authors have overall addressed my concerns, partially by answering the issues raised, partially by transforming their work into a Tools and Resources article.
Should this be accepted for publication, we would like to consider this as a Tools and resources article, a new category we are planning to introduce.
Your Tools and Resources article has been favorably evaluated by Aviv Regev (Senior editor), a Reviewing editor, and three peer reviewers.
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