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Randomized controlled trials (RCTs), and in turn systematic reviews (SRs) of RCTs, are considered the reference standard in resolving treatment uncertainties [ 1, 2].
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If the AE recurred at the reduced dose, treatment was held until the AE had resolved to ≤ grade 1 and when resolved treatment could be reinstituted at the next lower dose level.
Increases in IOP were mostly mild and transient, resolving without treatment in FVF2128g (Heier et al. 2006a).
Before initiation of treatment, there was anemia and marked leucocytosis which resolved following treatment.
Alternatively, patients whose hemoptysis resolves with treatment might consider themselves "cured" and hence stop treatment.
These are usually less severe infections and will often resolve without treatment.
If they invade via a break in the skin, the result is cutaneous anthrax, which often resolves without treatment and is easily cured by antibiotics.
The nodule completely resolved after treatment.
Again, the skin lesion completely resolved after treatment discontinuation.
The former will resolve without treatment; the latter will progress.
The patient's symptoms resolved after treatment with doxycycline.
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CEO of Professional Science Editing for Scientists @ prosciediting.com