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Furthermore, SV is highly complementary to other biophysical techniques for studying multisite protein interactions in solution, due to the potential of simultaneously resolving size and population of different coexisting states and can be quantitatively combined with data from isothermal titration calorimetry, surface plasmon resonance, and/or fluorescence polarization.
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Inline FBRM resolved size differences between different MCC grades, and the data correlated well with offline analyses.
Our SMPS could not resolve the small mode of the Fe2O3 particle size distribution and hence we resorted to the use of direct physical surface areas via the BET method, along with an analysis of the resolved size distribution of the larger particles to infer the contributions of each mode to number, surface area, and mass of the combined bimodal aerosol.
Milne et al. [ 121] created a more highly resolved size separation microfluidic system capable of segregating in flow as many as four sizes of silica spheres with diameter differences as small as 0.54 μm with a throughput of 40 particles per second [ 121].
As described in [ 48] MetaPhor agarose is capable of resolving microsatellite size differences of only two basepairs.
Finally, rotary shadowing and negative stain electron microscopy are powerful techniques for resolving the size and shape of single protein molecules and complexes at the nanometer level.
Due to the vagaries of resolving and sizing fragments > 1 Mb by PFGE, we estimated the size of the largest I-CeuI in the E. coli MG1655 genome to be 2.793 Mb, whereas it is actually 2.498 Mb according to published sequence [ 34].
Large computational resources are required to ensure sufficient accuracy to explicitly resolve aerosol size distribution spectra.
"CTA could resolve the size of the source: Is it really a point [source] or more extended?" Hofmann says.
This methodology enabled us to resolve (i) size variations of martensite sub-units, (ii) associated dislocation sub-structures, (iii) chemical heterogeneities, and (iv) the resulting local mechanical properties.
A cell test based on back extrusion was designed to evaluate the mechanical properties of a GMP paste and image analysis techniques implemented to resolve the size of GMP.
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