It remains unclear whether the etiology of the disc swelling was from slowly resolving inflammatory disc edema, corticosteroid-induced intracranial hypertension, or both.
Using a systems approach to mine spontaneously resolving inflammatory exudates, novel families of lipid- derived mediators were identified in animal systems that control both the duration and magnitude of acute inflammation.
Thus, appropriate, well-designed and fine tuned immune interventions that could resolve inflammatory responses and associated immunosuppression could enhance disease regression and reinforce successful responses to a given therapy.
Hardy and co-workers have demonstrated that mice lacking IL-12 infected with M. pneumoniae have less severe disease and rapidly resolve inflammatory changes in lung histology [15].
Resolvins are a family of new local mediators enzymatically generated within resolving inflammatory exudates.
Resolvins are a new family of local mediators that are present in resolving inflammatory exudates.
This is achieved by multiple mediators that initiate and modulate the extent and duration of and also resolve inflammatory processes.
One of the critical hallmarks of the endothelium is the ability to support and resolve inflammatory responses.
These nodules may be due to granulomatous disease, fibrosis, atypical adenomatous hyperplasia (AAH), bronchoalveolar carcinoma (BAC), adenocarcinoma, or slowly resolving inflammatory lesions.
