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The sequential approach adopted in PBL structurally reflects the daily work of medical doctors in terms of first defining problems and subsequently applying procedural [ 1] (i.e., differential) diagnostic pathways and/or explanatory (i.e., pathophysiological) models to resolve unclear issues [ 2].
Indeterminate results in positive samples were treated as negative and in negative samples were treated as positive since the application of NAT usually does not involve indeterminate endpoints, and laboratories should be able to resolve unclear results by double testing with another amplification assay (13 ).
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Thus, tissue engineering should resolve the unclear cell-scaffold relations and address the scaffold-associated outstanding challenges to ease the translation of tissue-specific cell-scaffolds constructs from laboratory to operating room.
Claudin-I immunofluorescence staining may resolve the unclear picture of the maintenance/loss of cell adhesion.
Further research is needed to resolve the unclear aspects of Norovirus transmission; thus, control measures could be adjusted correspondently.
Therefore, further research using larger patient populations and in vitro experiment may help to resolve the unclear results concerning this study.
Most agree that inflammation is a key initiator and driver of the disease, but what initial insult or factors drive this and why it does not resolve is unclear.
Just how the spending impasse will be resolved is unclear.
How differences with the House will be resolved is unclear.
How the dispute will be resolved is unclear, but it touches on domestic French politics.
The question, said Gary Taylor, an analyst at Banc of America Securities, is, "What is their real earnings power?" Exactly when some of these issues will be resolved is unclear.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com