In this regard, tethering of viral RNAs to chromatin may mimic aberrant RNA DNA hybrids reminiscent of R loops, a situation in which SUMOylation plays an important resolving role (Richard et al., 2013).
We resolved roles for early afterdepolarizations (EADs) and transmural gradients of repolarization in arrhythmogenesis in Langendorff-perfused hypokalaemic murine hearts paced from the right ventricular epicardium.
Due to the particularly large number of these ncRNAs, new high-throughput strategies are needed to test their function, since current mutagenesis approaches are unlikely to resolve their role.
Although additional studies are needed to fully resolve the role of GRN variability on the development of FTLD and related neurodegenerative disorders, these studies suggest an important role for PGRN dysfunction in a range of neurodegenerative diseases.
In March, Oppenheimer agreed to pay $2.8 million to resolve its role in the case.
Facebook paid Massachusetts regulators $2 million to resolve its role in the Facebook investigation.
In 2010, KeySpan, which is owned by the British energy company National Grid, paid $12 million to resolve its role in the case, also without admitting any wrongdoing.
Now under new management, Citigroup agreed to pay the government $285 million to resolve its role in the case, but the settlement has yet to receive court approval.
SAC also agreed Friday to pay $14 million to resolve its role in an insider trading ring that illegally traded technology stocks including Dell.
Mr. DeCinces and the three others settled the S.E.C.'s civil charges, with Mr. DeCinces agreeing to pay $2.5 million to resolve his role in the case.
