Sentence examples similar to resolve off-target effects from inspiring English sources

Whether candidate senolytics actually alleviate phenotypes though removing senescent cells or through possible off-target effects on nonsenescent cells is an important and difficult issue to resolve.

It absolutely minimises off-target effects".

Despite its potential, PDT can suffer from off-target effects.

Monitoring off-target effects of the CRISPR-Cas9 system.

Of the two potential off-target sites we examined, no off-target effects were observed.

We reasoned that the proxy-CRISPR targeting strategy can be applied to reduce off-target effects.

These therapeutic approaches target nucleic acids, and off-target effects represent a serious concern.

Inhibition was achieved without inducing cytokines or off-target effects.

Moreover, each technology exhibits its own set of off-target effects and limitations in on-target efficacy.

Targeting the genome with sequence-specific small molecules may enable molecules with increased therapeutic index and fewer off-target effects.

In contrast, three diced siRNA pools against p38alpha MAPK had almost no off-target effects.