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However, this density was not fully resolved, likely due to heterogeneity, both conformational and biochemical, in the data.
The precise branching order among paralogs was not fully resolved, likely because the number of informative amino acid sites was relatively low (supplementary fig. S8, Supplementary Material online).
Taking impetus from this, we tested a range of pharmacological blockers as a first step in resolving likely Kv channel components underlying the A-type K+ current in retinal arteriolar myocytes.
While the mechanism by which different concentrations of the nuclear transcription factor complex translate into different transcriptional responses has not been resolved, likely mechanisms include promotor selection based on differences in the promoter binding-site affinities, cross-repression, and the establishment of a reciprocal of repressor gene expression [ 36, 37].
That resolve is likely to be tested again this week, however, with Chelsea expected to offer in the region of £30m for a player José Mourinho envisages as the long-term replacement for John Terry.
While U.S. and European sanctions have been reauthorized, at least through the first half of 2017, a weakening of European resolve is likely if the new administration indicates a reluctance to keep them in force.
While they remain determined to keep their prized asset, who scored 30 goals for the club in 44 appearances last season, their resolve is likely to be tested if the bidding continues to rise.
While Liverpool remain determined to keep Suarez, who scored 30 goals for the club in 44 appearances last season, their resolve is likely to be tested if the bids continue to rise.
But resolving the differences between the United States and the Afghan government, if they are resolved, is likely to have a profound effect on the long-term commitment of other NATO members.
Until these challenges are resolved, it likely will be difficult to maintain effective disease management programs for CKD.
But the way that this debate is resolved will likely have some major repercussions for global economic policymaking.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com