Furthermore, the distance of these adjacently positioned regions of 'inferred LOH' from 'conventional LOH' was determined primarily by the resolution of markers within each respective genomic region.
This process has likely been overlooked in previous genetic crosses and population studies due to lower resolution of markers and the short nature of these double crossovers.
As the densities and resolution of markers in the Atlantic salmon linkage maps increase, and the sequencing and assembly of the salmon genome advance, the extent of such rearrangements will be better resolved.
These studies were mostly based on microsatellite loci and/or sequence variation at candidate genes and consequently their conclusions were limited by the low number and resolution of markers or genomic regions.
- The sentence starting with " The detection of genetic structure largely depends on the type and number of molecular markers examined ": Here you may want to mention explicitly the temporal resolution of markers with different mutation rates (as you have done in the Discussion).
Several studies pointed out the relevance of integrating secondary structure information in sequence analysis and phylogenetics, both in terms of phylogenetic resolution and of marker suitability for phylogenetic reconstruction at higher taxonomic-rank.
Although Pan et al. (2015) and Fujino et al. (2015) recently reported the association mapping of cold tolerance QTLs in rice, the low resolution of SSR marker genotyping data affects the interval distance of the mapped QTLs.
The depth resolution of Alq3 marker layers embedded in an NPB matrix is ∼10 nm as shown in Figure 3.
Depending on the resolution of the marker, a few closely related taxa such as A. pedemontana, A. cebennensis and A. croatica are also clearly distinct evolutionary lineages.
