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All six patients had resolution of infectious keratoscleritis; unfortunately, more than half of these patients required corneal transplant, cataract extraction, glaucoma aqueous shunt, or some combination of these surgical treatments.
With regard to temperature, leukocytosis and PaO2/FiO2, Dennesen and colleagues [ 29] already described the resolution of infectious parameters after initiation of appropriate therapy for VAP in 27 patients.
Therefore, when the patient is his or her own control (that is, a relative variation in the same patient is considered a marker for clinical response), we may control for the potential differences secondary to different base-line inflammation response level and assess the variation occurring according to the actual resolution of infectious stimulus.
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This shows the resolution of the infectious crystalline keratopathy, corneal stromal infiltrate, anterior chamber reaction, and conjunctival injection with no signs of graft rejection.
Haematological assessments were made twice weekly, or every 2 days in cases of febrile neutropenia until recovery to grade⩽1 neutropenia and resolution of all infectious symptoms.
Nonetheless, in the onset of sepsis increased oxidative metabolism was probably involved in resolution of the infectious course, but in the late stages of sepsis it was associated with tissue damage and, consequently, organ dysfunction and death.
In pregnancy, proteinuria was not limited to the phase of active infection in any patient, as it persisted or even developed (cases 4-5-6) after resofuthen of the acute infectious phase.
Recent applications of whole-genome sequencing (WGS) have demonstrated exceptional resolution that enables fine delineation of infectious disease outbreaks (7 – 10 ).
The importance of NGS in ascertaining high-resolution phylogenetic and molecular epidemiological histories of infectious outbreak clones of bacterial pathogens has recently been noted [ 18, 20].
The use of molecular markers has provided greater resolution in the characterisation of the spread of infectious disease.
Monocytes can differentiate into dendritic cells and macrophages and are crucial for the initiation of an adaptive immune response, clearance of infectious agents as well as resolution of inflammation.
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