Analog sound, said Amos Gaynes, Moog Music's applications engineer, has infinite resolution, "down to the granular level at which reality is perceived".
New modalities such as single-bunch imaging provide a time resolution down to the nanosecond for radiography [41].
The main features of the MPGDs are: high rate capability (>50 MHz/cm2); excellent spatial resolution (down to 50 μm); good time resolution (down to 3 ns); reduced radiation length, affordable costs, and possible flexible geometries.
In this case, thanks to the use of recent turnkey Raman systems, one can perform fast mapping with spatial resolution down to 300 nm.
Three-dimensional structure of PsbO from cyanobacterium Thermosynechococcus was resolved as a part of PSII by X-ray crystallography with a resolution down to 1.9 Å [ 5].
Resolution down to a few tens of nanometers is achieved by Stochastic Optical Reconstruction Microscopy (STORM) [51] and Photoactivated Localization Microscopy (PALM) [52,53].
In parallel, modern multidetector CT scanners can generate data with unprecedented spatial resolution (down to 0.5 mm), with a consequent enormous increase in image number; therefore, manual reading of CTC images may become error-prone due to reader fatigue.
Examples include Illumina HumanMethylation 450 K beadchip [ 3] for the former, and whole genome short-gun bisulfite sequencing (GWSBS [ 4]) and reduced representation bisulfite sequencing (RRBS [ 5]) for the latter, all offering fine resolution (down to the single nucleotide).
Copy number analysis by sequencing (both by high or low coverage) offers substantial benefits over array-based methods, including higher resolution (down to a single base) and precise delineation of breakpoints [ 72, 73].
In the last several decades, numerous biomedical imaging techniques were developed, ranging from the whole organism level (millimeter resolution) down to the single molecule level (nanometer resolution) (Murphy, 2001; Tsien, 2003).
