Sentence examples for resistant to development from inspiring English sources

IL-17 deficient mice or mice treated with an IL-17 receptor antagonist are resistant to development of CIA and develop EAE with delayed onset and reduced severity [ 16, 43].

Moreover, in mice transgenic for the RA susceptibility gene HLA-DQ8, CD4-deficient mice were resistant to development of CIA whereas CD8-deficient mice developed disease with increased incidence and greater severity [ 23].

People living in south-west England, West Midlands and Scotland appear most resistant to development, while Wales and the north-east are least opposed.

For this reason, Egyptian art appears outwardly resistant to development and the exercise of individual artistic judgment, but Egyptian artisans of every historical period found different solutions for the conceptual challenges posed to them.

With regard to chemically-mediated skin carcinogenesis, Stat3-deficient mice were completely resistant to development of skin tumors induced by the two-stage carcinogenesis regimen and abrogation of Stat3 function by using a Stat3-specific decoy oligonucleotide inhibited the growth of skin tumors [10].

The protection of PLCγ2−/− mice from induction of arthritis was not due to absence of mature B cells, since PLCγ2−/− mice adoptively transferred with WT B cells (Figure S1) were still resistant to development of the disease (Figure 1E,F and 2A,B).

Under-nutrition during late gestation and early post-natal development led to adults who were resistant to the development of obesity.

This would be expected to make A/J mice more resistant to the development of anaemia but since all strains developed anaemia at a similar rate in our experiment, the complement cascade may not be an important participant in this process.

Mice deficient in A-FABP are resistant to the development of hyperinsulinemia, hyperglycemia and insulin resistance [ 18].

Mice with complete inactivation of TNF or TNFR1 gene are unable to mount a protective response against various pathogens [15], but develop ECM, while TNFR2 deficient mice are resistant to ECM development [16].

Furthermore, Skp2 −/− mice are more resistant to the development of obesity and obesity-related insulin resistance induced by a high-fat diet or by the lethal yellow agouti mutation, likely due to inhibition of the increase in adipocyte number.