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This concept states that animals that are infected with a pathogen may vary in their response, which can be one of complete resistance, i.e. animals are resistant to developing symptoms of an infection.
In infectious disease models, the concept of tolerance (T) and resistance (R) states that animals that are infected with a pathogen may vary in their response, which can be one of complete resistance, i.e. animals are resistant to developing symptoms of an infection or vary in tolerance, such that the symptoms that develop after infection can be severe or mild [9].
Another said that the administration was resistant to developing a "grand theory for a weapon whose possibilities they were still discovering".
The relevance of this concept is in part based on investigations that have discovered that genetic 'knock-out' mice incapable of expressing IL-1 RI (80-kDa) or TNF RI (55-kDa) receptor complexes are highly resistant to developing the pathophysiological alterations classically associated with conditions of endotoxic-shock.
Despite their innovation of putting the engine behind the driver, the Coopers and their Chief Designer Owen Maddock were generally resistant to developing their cars.
To determine why the Snord116del mice are resistant to developing obesity, we carried out more detailed analyses of their feeding behavior and metabolism.
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Similarly, most dog strains are relatively resistant to develop atherosclerotic disease.
The identification and utilization of new sources of resistance to develop SCN-resistant varieties have been demonstrated to be most efficient and practical manner to control this nematode.
For example, accessions of Vitis aestivalis, V. arizonica, V. shuttleworthii, and V. smalliana are highly resistant to PD [ 2], and breeding programs have utilized these resistant species to develop PD resistant grapes for the southeastern United States [ 3].
Compared to B6.apoE-/ mice, BALB.apoE-/ mice are highly resistant to atherosclerosis, developing much smaller lesions.
"If you make repeated sprays over years, there is potential for resistant populations to develop," he said, referencing the well-known resistance resulting from the ongoing use of pesticides in Africa to combat malaria.
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