The Fusarium wilt-resistant processing variety Marvel [ 10] was selected from Merville des Marchés in the early 1900s, and Marvel was a parent of Marglobe released in 1925 [ 11], which in turn can be found in the pedigree of many important varieties from the 1930s through the late 1950s (H.M. Munger's tomato pedigree chart provided by E.D. Cobb, Cornell University, 2012).
In related studies Ira Mellman's lab showed that protein antigens that were resistant to processing were better immunogens compared with more easily processed antigens [63].
One hypothesis is that a non-lethal infection of a population with IPN could result in the more resistant fish processing or depositing pigment differently to the susceptible fish, resulting in downstream differences in flesh colour that can be explained by the IPN QTL genotype.
Certain mycotoxins do not readily degrade at high temperatures, therefore are resistant to food processing, and consequently are present in the human and animal food supply.
Unlike most precursor proteins, the ADAMTS9 zymogen (pro-ADAMTS9) is resistant to intracellular processing.
These juxtamembrane ErbB4 isoforms are either susceptible or resistant to proteolytic processing that release a soluble receptor ectodomain.
This is further supported by the fact that the ciliary localization of Gli2 variants resistant to proteolytic processing is also efficiently inhibited by forskolin treatment (Fig. 4C, see below).
The JM-ErbB4 isoforms differ within their extracellular juxtamembrane domain annotated as based on differential inclusion of exon 15 (JM-a) or exon 16 (JM-b), which renders them susceptible or resistant, respectively, to processing by matrix metalloproteases [9], [10].
It is also resistant to subsequent processing with photolithographic chemicals and solvents.
Selecting biomarkers resistant to sample processing variation led to robust lung cancer biomarkers that performed consistently in independent validations.
