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Resistant mutants are very rare, except for vancomycin-resistant Enterococcus.
Different Ciprofloxacin concentrations selected different low level resistant mutants, and high level resistant mutants emerged from low level resistant mutants if stressed further by Ciprofloxacin.
The two low level resistant mutants had different molecular mechanisms.
The 3H4MV content in leucine analog resistant mutants was measured by high-performance liquid chromatography (HPLC).
The selection of resistant mutants provided strong support for LepB as the target of these compounds.
They also have high potency against ALK resistant mutants, especially the gatekeeper mutation ALKL1196M.
Similar(23)
Many auxin-resistant mutants display ethylene resistance in root elongation.
Cross-resistance levels of Stl-resistant mutants and CBR703-resistant mutants (mutations on pRL706 and pRL663 derivatives; Tuske et al., 2005; X Wang and RHE, unpublished) were determined analogously to resistance levels of induced Sal-resistant mutants.
Resistance levels of Sal-resistant mutants were quantified by performing broth microdilution assays.
Resistance levels of GE-resistant mutants were quantified by performing broth microdilution assays.
Triclosan-resistant mutants of Escherichia coli and Staphylococcus aureus have already been isolated in the laboratory.
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