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When in balance, this microbiota acts as a barrier against potential pathogens and resistant microbes (colonization resistance) [ 18, 19].
In the past, resistance could be handled by development of new drugs active against resistant microbes.
As deaths due to resistant microbes are generally associated with healthcare-associated infections (HAI), antibacterial resistance could be responsible for up to half of HAI deaths.
The prevailing theory on how resistance develops posits that reckless antibiotic-prescribing practices drive the evolution of resistant microbes.
The resistant microbes they create can spread to humans.
Avoiding unnecessary treatment eliminates the risk of adverse side effects and development of resistant microbes.
Similar(25)
The result is nearly the same as if we were eating the antibiotics ourselves: an increase in antibiotic resistance in humans and the emergence of drug-resistant microbes.
The World Health Organization's report on the alarming increases in drug-resistant microbes (editorial, June 18) should cause concern in the wealthiest nations and the poorest.
In recent years, the rise of drug-resistant microbes has made the antibiotics we use less effective and has increased the risk that an infectious disease could get out of control.
Perhaps most important, a growing number of health experts worry that the widespread use of antibiotics in agriculture, particularly in poultry operations, is leading to the growth of drug-resistant microbes that could cause severe problems for human health.
Recently, researchers in Israel, where most citizens receive their care through such a system, showed that refraining from empirically prescribing antibiotics during the summer months resulted in a sharp decline in ear infections caused by antibiotic-resistant microbes.
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