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A well-defined panel of cisplatin-sensitive and resistant EC cell lines 833KE, Tera, Tera-CP, Scha, and 2102EP (all expressing wild-type p53) and NCCIT (mutant p53) were used in this study.
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Both topographical and mechanical factors should thus be considered when designing vascular grafts to enhance the flow-resistant EC adhesion.
We demonstrated that micropattern alignment parallel to the flow direction enhanced flow-resistant EC adhesion, while micropattern alignment perpendicular to the flow direction attenuated it.
EC apoptosis has been implicated as an initiating event in experimental PAH, leading either directly to the degeneration of pre-capillary arterioles or to the selection of hyperproliferative, apoptosis-resistant ECs that may contribute to "angioproliferative" plexiform lesions.
Due to the enhancement of ozone (O3) transformation to hydroxyl radicals by electro-generated H2O2, the E-peroxone process can considerably enhance the efficiency and reduce the energy consumption for the abatement of ozone-resistant ECs compared to conventional ozonation.
Considering that LPS-resistant ECs exhibit a fibroblast-like morphology, suggesting that these ECs enter in a fibrotic program in response to LPS, our aim was to investigate whether LPS induces endothelial fibrosis and explore the underlying mechanism.
The results shown that, the CNi was the more EC resistant coating under most of the experimental conditions, at 5 m/s the EC degradation mechanism was dominated by matrix degradation with the WC showing little damage and the CFe was negatively affected by corrosion, especially at 65 °C.
All patients, from whom a clinical specimen yielded a KP or EC isolate resistant to Colistin (VITEK2 COMPACT,bioMerieux, Hazelwood, MO).
In contrast to hydrogen peroxide, DAC N-055 is catalase (EC 1.11.1.6) resistant [ 24].
Despite this, some BCL2 High NHL cell lines are relatively resistant to venetoclax, with EC 50 s >2 μ M in vitro, a facet we hypothesized here to be a consequence of MCL-1 function and not simply expression.
Although interactions between LPS and ECs evoke endothelial death, a significant portion of ECs are resistant to LPS challenge [ 6- 8].
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