Sentence examples for resistance site from inspiring English sources

As summarized in Figure 2, each drug resistance site was probed with an RCO-BCO set (typically one BCO for the mutant sequence, one BCO for the wild-type sequence and an RCO which can be ligated to either the mutant or wild-type BCO).

We were able to make accurate predictions without the resistance site information available in the literature.

Two, only positive samples were analyzed for subtypes and drug resistance; site prevalence analysis of HIV in the studied population was not possible.

Here we describe recent changes in the distribution of M. tuberculosis genotypes in New South Wales (NSW), Australia and compared strain types with drug resistance, site of disease and demographic data.

Figure 5C, showing the BM classification method, reveals the resistance site M36 as a consistent indicator for negative response and ELM-Lig-SH2-STAT 5 as a strong indicator for positive response to antiretroviral therapy.

A third resistance site (GyrA-81) is not expected to directly participate in metal ion coordination, but a GyrA-G81C resistance substitution has been proposed to interfere with ion binding indirectly by sterically perturbing the geometry of the gyrase acidic group at a distance.

We also note that the presently detected positions 47 and 48 in the flap region do not appear in the study by Wu et al. as prominent drug resistance sites, but they are known to be major resistant mutations.

At the final stages of DNA binding and cleavage (Figure 5C), the quinolone resistance sites (Ser 79 and Asp 83, which are located within the helix α4 bound to the minor groove of the DNA molecule) will be positioned next to the 3'-end of the cleaved DNA strand with Ser 79 being closest to the point of cleavage (Figure 5C).

Several minor mutations were found at five different drug resistance sites.

These features corresponeded to two specific resistance sites (RS)s and ELMs.

Some of these predictive motifs overlap with known HIV-1 resistance sites.