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The structural system is designed using member consequence factors as additional partial factors on the resistance side of the design equations.
Novel targets for the management of HIV infection have become increasingly relevant in view of extensive drug resistance, side effects and high pill burden of some of the conventional anti-retroviral agents.
The paper provides a framework for future rigorous reliability theory-based LRFD calibration for the ultimate tensile rupture of geogrid reinforcement in reinforced soil applications in Japan and elsewhere, and provides the necessary bias statistics for the resistance side in the ultimate tensile rupture limit state equation.
The factors on the resistance side are the discrepancies between real and design yield stress, the value of through thickness resistance of steel, the need for requirements on toughness of the base and weld material and the effect of strain rate.
However, these DAAs have a low genetic barrier to resistance, side effects, potential for drug drug interaction, and are costly.
You may still have fears around resistance, side effects, abuse, misuse and access.
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However, drug resistance and side effects have limited their clinical utility.
The drugs currently employed have limitations such as poor efficacy, drug resistance or side effects.
Nevertheless, many cancer patients cannot be cured from their disease because of the development of drug resistance and side effects.
However, because of a lower total resistance, this side hull form could be adopted at lower Froude numbers.
Most poor countries lack the laboratory capacity to conduct the necessary blood tests to measure drug efficacy and monitor for resistance and side effects.
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