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For mRNA residing peaks, about 45% of the peaks located in the 3'UTRs, about 35% in the CDS, and only less than 20% from the 5'UTR.
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However, there are no true peaks residing in this regions.
If the peaks resided within 5000 bp of TSS they were called as "promoter" peaks.
Upon ORCA depletion, most of the affected H3K9me3 peaks resided in late-replicating domains.
If the peaks resided in intragenic region of nearest gene it was called "intragenic", otherwise "intergenic".
To our surprise, 607 out of 707 of these peaks resided outside of the domains described previously (Gassmann et al., 2012) and corresponded to sites of only slight local cenH3 enrichment in the X-ChIP data.
In brief, imagining genetic variation displayed on a topographic map, Wright depicted the more "harmonious" gene combinations (i.e., better adapted organisms within a population) as residing at or near the "peaks," and less well-adapted organisms to occupy positions on the slopes or even in the valleys, between peaks.
It is well known that the ionosphere, a conductive, ionized region of the Earth's atmosphere, exhibits significant variations in the peak plasma density residing typically in a relatively thin layer (200 400 km) in the F-region.
To identify candidate cancer modifier genes in the Lsktm1 locus, we analyzed the pulmonary expression of genes residing near the LOD score peak, assuming that the SNPs associated with lung tumor multiplicity can regulate in cis the expression of Lsktm1 genes, as has been shown for loci associated with other diseases (Libioulle et al. 2007; Moffatt et al. 2007).
In agreement to Figure 8, the path length peak resides between 2 and 4. Thus, we conclude the characterization of the mesoscopic features of the community structure discussing the distribution of weights and strength of links among communities.
We acknowledge that the large distance between peaks for the eye and VAB QTL on LG2 may not provide the most convincing evidence for pleiotropy or hitchhiking under the assumption that the responsible mutations reside under the peak of each QTL; however, we only assume that they fall somewhere within the QTL's 95% confidence limits.
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