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Tumor ECM significantly impairs the diffusion of the chemotherapeutics impeding the adequate treatment of cancer cells that reside distantly from the blood vessels.
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The data indicate that the epigenetic response to maternal care involves not only single candidate gene promoters but includes transcriptional and intragenic sequences, as well as those residing distantly from transcription start sites.
pylori, Wolinella succinogenes and C. jejuni), it is likely ancestors of these distantly related organisms resided in a common environment and acquired similar T4SS genes from one or several progenitors.
CAK function instead resides in Cak1, a monomeric kinase only distantly related to CDKs [5] [7].
Similarities of Rickettsia VirB7/VirB9 to ComB7/ComB9 proteins of ε-proteobacteria, as well as phylogenetic affinities to the Legionella lvh T4SS, imply the Rickettsiales ancestor acquired a vir-like locus from distantly related bacteria, perhaps while residing in a protozoan host.
Second, highly related OR genes are tightly clustered in the zebrafish genome, with the members of a given subfamily residing adjacent to one another, uninterrupted by more distantly related genes [ 18, 33].
Major part of isochore resides in noncoding genomic regions, which are in general not alignable between distantly related species like human and mouse.
We found that gene pairs reside on duplicated zebrafish chromosomes, and these duplicated chromosome segments are shared with the pufferfish fugu, suggesting that distantly related teleosts share an ancestral genome duplication event (Postlethwait et al. 1994, 1998, 1999, 2002; Amores et al. 1998; Taylor et al. 2003; Jaillon et al. 2004).
"No," she says distantly.
(And distantly imagining the act of wearing).
"Sleater-Kinney?" she says distantly, and frowns.
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