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Exact(4)

Also, we have to take into consideration the contribution of GSH conjugation with prooxidants and the hindrance of GSH reservoir replenishment due to the GR unchanged activity (Figure 7).

Evaluation of each individual case revealed no correlation between serostatus or initial proviral reservoir size and the extent of reservoir replenishment or time to viral rebound.

In this study, we calculate the well-known replication threshold below which infection cannot be sustained [ 40] for our model, and discuss latent reservoir replenishment above and below this threshold.

The analysis of the effects of interruptions on the dynamics of viral reservoir indicates that very low reservoir size is not a prognostic marker of long-lasting HIV remission and that reservoir replenishment driven by viral rebound may be fast and irreversible even in these cases.

Similar(56)

Clonal B-cell reservoirs may be a source of replenishment for OCB-producing B cells; such reservoirs may be located within the CSF, in meningeal lymphoid folliclelike structures, 11 intraparenchymal B-cell infiltrates, or the periphery.

Japan's population doesn't have that source of replenishment.

Stem cell reservoirs are available for replenishment of the tissue in tissues in human body.

Evidence for replenishment of the reservoir in the setting of HAART comes from clinical studies showing accelerated reservoir decay for patients on an intensified HAART regimen over that observed in patients on standard HAART regimen [ 10, 19, 20].

On the other hand, replenishment of the reservoir might also become irreversible, as depicted by the sustained level of total HIV-1 DNA in Pt03 during the 3 years after discontinuation.

Continuous replenishment of the reservoir may occur through ongoing virus production (Hatano et al., 2013; Buzon et al., 2010), perhaps in sites where ART penetration or activity is suboptimal (Fletcher et al., 2014).

Although the mechanism of HIV persistence is not fully understood, proposed models focus on the continuous replenishment of the reservoir through ongoing virus production, perhaps in sites where ART penetration or activity is suboptimal.

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