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Most neurons with NF-L accumulation resembled intact neurons, whereas only little NF-L immunoreactivity was found in tangles.
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BER searches also identified genes that contain a frameshift within a polyA or polyT tract but otherwise resemble intact genes.
In recent times, work by Clevers' group and others has led to the development of three-dimensional culture systems, which allow the culture and growth of intestinal stem cells, eventually forming organoids resembling intact mature intestinal epithelial layers in their cellular composition and function.
Knee kinematics during flexion following UKR has been shown to more closely resemble the intact knee.
But that changed after the researchers gently pressed the hair into the surface and then began to drag it across and nearly parallel to the sensor--movements that resemble how intact setae work as the gecko puts its foot down.
Even though the BBTB is considered 'leaky' in the core part of glioblastomas, in large parts of glioblastomas and, even more so, in lower grade diffuse gliomas the BBTB more closely resembles the intact blood brain barrier (BBB) and prevents efficient passage of cancer therapeutics, including small molecules and antibodies.
Although the cell density of the BM-like tissue is slightly low, sections of the organoids resembled those of intact BM tissue.
Short-term administration of estradiol alone initiated epithelial proliferation, characterized by the presence of numerous side buds; however, when progesterone was administered with estradiol, the effects of ovariectomy on the PR-A phenotype was fully reversed such that the hyperplastic mammary phenotype resembled that of intact mice.
In the area immediately surrounding the channel, the fibrocartilage cells and the collagen matrix arrangement remained intact and resembled the control untreated disk tissue.
Prior to modification, Fab' A5B7 (M r) 50,000) cleared more rapidly from the circulation than F ab' 2 (M r) 100,000), but after PEG attachment their biodistributions converged, while the tumour to blood ratios were reduced and resembled that of the intact antibody.
Although these shapes do not achieve the complexity observed for our fibre scaffolds, the tight packing of the diverse carrot cells within the pores does resemble a simple intact tissue.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com