Therefore, we conclude that the TM7−HX8 segments in both of these GPCR crystal structures resemble active-like conformational elements.
Moreover, the characteristic DEDHD residues in protist MAEL domains are clustered into a structural core, which resembles active sites of DnaQ-H domains.
Furthermore, the occurrence of disease resembling "active trachoma" in noninfected individuals living in communities that are or have recently been trachoma endemic is well documented (13, 42) and is the subject of ongoing research.
Decoys in DUD-E were chosen to resemble the active ligands in terms of their physicochemical properties whilst being topologically dissimilar to minimize the likelihood of actual binding [22].
These three states closely resemble (i) active growth; (ii) starvation; and (iii) environmental stress.
The same research group also reported that irradiation of the 2,5-dimethylbenzoyl oxiranes 18 results in a relatively efficient and high-yield formation of β-hydroxy-functionalized indanones that structurally resemble biologically active pterosines (Scheme 10).
In addition, a homology model of c-Src kinase with the activation loop resembling the active conformation was constructed using the crystal structure of the kinase domain of Lck.
It is found that Co/MoS2 resembles FeN4 active site while Ni/MoS2 is similar with CoN4 active site.
This paper proposes a strategy for object recognition resembling the active template matching strategy in chickens.
Compound 1 represents the first example of a 3D-framework containing the oxygen-bridged dinuclear secondary building unit {Zn2 dmf)(H2O)(μ2-RCOO)2(RCOO)2}, which resembles the active centers of dinuclear zinc enzymes.
