Secondary efficacy endpoints were change in fasting plasma glucose (FPG) from baseline over time, time to hyperglycaemia rescue, the proportion of patients meeting HbA1c treatment goals (<6.5% [<47.53 mmol/mol] and <7.0% [<53.00 mmol/mol]) and body weight change from baseline over time.
Our data support a potential role for Hh signalling in reducing the impact of TCR signals as we show that Hh signals can limit the production of SP cells in TCR transgenic models, attenuate the development of high affinity DN T-cells and rescue a proportion of T-cells from Mtv-mediated deletion.
This screen identified 10 different hit compounds that partially rescued the proportion of GFP+ cells when assayed by high-throughput FACS analysis.
CFE was stimulated by CS in tumour immunized rats; the inflammatory state did not prevent the expression of immunity but "rescued" a proportion (approximately 20%) of the injected tumour cells from immunodestruction in the lungs.
He was thus able to rescue a high proportion of the units involved, albeit at the cost of nearly all their armour and heavy materiel.
Advances in medical and ventilatory management of severe lung injury and ARDS have improved outcomes in some patients, but these advances fail to consistently "rescue" a significant proportion of those affected.
A rescue in the proportion of CD4+ DCs was also seen when Cyp7b1 −/− mice were reconstituted with BM from transgenic mice (Ngo et al., 2001) that overexpress LTα1β2 on B cells.
Consistent with the DC-deficiency being a consequence of reduced LTβR signaling, treatment for 6 days with an LTβR agonistic antibody (De Trez et al., 2008; Stanley et al., 2011) led to a significant rescue in the proportion of CD4+ DCs present in the spleen.
However, for valuable field samples that are associated with important demographic, clinical and other phenotypic data such as drug resistance or vaccine resistance [ 16], microarrays can rescue the high proportion of samples that fail to meet criteria for sequencing, justifying the use of microarrays.
The toad patrols — there are about 100 of them in Britain — are rescuing a substantial proportion of the toad population from vehicular death.
