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As a result, large drug companies have shied away from the rescue approach and progress has been slow, he says.
Objective: The purpose of this study was to compare the neonatal outcome of 2 approaches to antenatal corticosteroid therapy for threatened preterm delivery in twins: a prophylactic approach in which corticosteroids were administered every 2 weeks from 24 to 32 weeks of gestation and a rescue approach in which corticosteroids were given to women at immediate risk of preterm delivery.
Thirdly, using a conditional complementation rescue approach, we generated an HIV-1 construct containing 80% TC-labeled NC proteins.
To answer such questions and gain more insight into the in vivo function of endophilin-A BAR, we adopted a mutant rescue approach in Drosophila.
To test whether this hypomorphic allele is responsible for the otoxray mutant phenotype, we used a BAC (bacterial artificial chromosome) transgenic rescue approach.
To investigate the basis for functional differentiation between synaptotagmins-1 and -7, we used a rescue approach with autaptic hippocampal glutamatergic neurons from synaptotagmin-1 KO mice.
Similar(36)
But even as rescue approached, many were too terrified to come out of hiding.
In recent years, the pursuit for novel rescue approaches that are effective in diabetic ischemic myocardium has significantly increased.
At this point in time, CSF therapy should thus be applied in the context of clinical trials only, with the exception being individual off-label rescue approaches.
Both the pharmacological antagonist of PATs 2‑bromopalmitate and shRNA knockdown or rescue approaches are widely used to explore the roles of specific palmitoylation events.
A more complex genome engineering approach would have to be employed to delete the whole duplicated region and subsequent transgenic rescue approaches performed to assign specific functions (if any) to Rhox2, Rhox3 or Rhox4.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com