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Overcoming an ingrained perception that one is intellectually defective can be a requisite step in this process.
Publication of research findings in recognized peer-reviewed journals is a requisite step in this process.
Thus, under hypoxic stress, inactivation or loss of VHL function appears to be an early and requisite step in tumor development.
Since escaping senescent-cell death could be a requisite step in neoplastic transformation, it is important to establish which the inducers of the autophagic programmed cell death encountered by senescent cells are.
Cell cycle re-entry and DNA replication in endothelial cells is a requisite step in angiogenesis.
Hence, C2 halogenation of heteroarenes is often a requisite step in drug synthesis.
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Proof-of-concept and trials like this one are also requisite steps in getting to a point where UPS is actually using this tech live in the field where it could genuinely help.
Importantly, the presence of an actin cytoskeleton and the ability to generate contractile forces are requisite steps in the response of cells to their environment.
Identifying and accessing the relevant data are requisite steps in being able to use these methods.
In this original report and all of the many biological and biomedical studies that have followed, the conversion of XDH to XO has been considered to be a requisite step for activation of oxygen free radical generation in postischemic tissues.
Therefore, global sharing of skills in systematics and biodiversity informatics is a requisite step for true globalization of the community and the science.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com