Sentence examples for requisite role of from inspiring English sources

Still others represented reconstructive epistemological projects in response to such findings, arguing for a requisite role of values in scientific theorizing, or arguing that rational investigation requires a critical assessment of the metaphysical (and sometimes gendered) assumptions underlying a field of study.

Our studies also reveal that Puma upregulation induces cell apoptosis in chemoresistant ovarian cancer cells, confirming the requisite role of Puma in chemosensitivity.

The requisite roles of islet-specific autoreactive T and B cells have been well established and have been the primary target of current clinical investigations [2], [3], [4], [5].

Moreover, studies summarized above have demonstrated a requisite role for progesterone in the induction of mammary cancer development by E2 in ACI rats [ 13, 19].

The inability of rhBCL2A1 to protect the TLR2−/− or MyD88−/− mice against I/R injury of skeletal muscle indicates a requisite role for TLR2-MyD88 signaling for cytoprotection in vivo.

However, CyanM4 did not modify CyanA1.2 (Supporting Information Figure 23), supporting the model that it is the cognate leader peptide (i.e., the leader peptide of CyanA4.1) that plays a requisite role for enzyme catalysis, although probably not for substrate promiscuity.

As previously reported for ischemia-reperfusion injury [26], we found that administration of rhBCL2A1 failed to protect TLR2-null mice from sepsis-induced mortality, indicating that there is a requisite role for TLR2 signaling for the protective effect in vivo.

On the other hand, S6K1 is known to play a requisite role in the regulation of autophagy in Drosophila [ 28], making it a promising candidate for the in vivo target of resveratrol that is responsible for inhibition of autophagy.

It has been reported that dipeptidyl peptidase I (DPPI) is a granule protease that plays a requisite role in processing the proenzyme form of the cytotoxic T-lymphocyte (CTL) granule serine proteases (granzymes) [19] [22].

Sequential upregulation of these two proteins plays a requisite role in providing costimulatory signals required for efficient B-cell antibody production and isotype class switching [ 42, 43].

The current results suggest that the discovery of the semantic (animate-inanimate) distinction and its requisite role in the AMR was crucial for accurate generalization to new items.