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The adhesion is thought to be a pre-requisite for differentiation to the infective form, but less is known about how epimastigote adhesion triggers the differentiation process after the nutritional stress [40].
Minimal requisites for chondrocyte differentiation include a 3D environment, serum withdrawal, and addition of dexamethasone, vitamin C, and transforming growth factor- β [ 10].
Recently, it has been suggested that IL-6 induces the upregulation of the IL-1R and that this effect is a pre-requisite for the differentiation of Th17 cells (Chung et al., 2009).
Interactions between stem cells and extracellular matrix (ECM) are requisite for inducing lineage-specific differentiation and maintaining biological functions of mesenchymal stem cells by providing a composite set of chemical and structural signals.
The scaffolds have been characterized and tested as supports for both osteoblast growth and pre-osteoblast differentiation, as fundamental requisite for their potential use in bone tissue engineering.
Language provides more opportunities for differentiation.
The grid is a useful device for differentiation.
"We are desperate for differentiation from the Tories," one Lib Dem strategist told me.
There are also opportunities for differentiation in pricing.
Qatar's strategy for differentiation is their 'compact bid'.
For example, DNA methylation is requisite for HSC self-renewal and deficiency of methylation leads to differentiation into myeloerythroid cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com