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In mammalian cells, Smo-dependent signaling requires translocation to primary cilia.
It has been reported that mitochondrial fission requires translocation of Drp1 from the cytosol to mitochondria.
Agonist-dependent desensitization of the beta-adrenergic receptor requires translocation and activation of the beta-adrenergic receptor kinase1 by liberated Gbetagamma subunits.
Whether plastic mechanisms in HU rats requires translocation of ERK1/2 to the nucleus remains to be determined.
NADPH oxidase activation requires translocation of the cytoplasmic subunits p47phox, p67phox, and p40phox and rac to the membrane-bound flavocytochrome consisting of gp91phox and p22phox (phox, phagocyte oxidase).
Long-term treatment with NAC affected NFκB signaling in the brain by increasing cytoplasmic retention of NFκB (Fig. 5) thus preventing its action as a transcription factor, which requires translocation to the nucleus.
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This observation indicates that entering termination at these locations does not require translocation of the RNAP along the DNA.
These results show that, although β-catenin and eNOS co-associate in the plasma membrane, β-catenin translocation to the nucleus following eNOS activation (at least by agonists that do not raise intracellular Ca2+) does not require translocation of eNOS.
In addition, relative to Options 3/5, the use of a single hatchery facility with Options 2/4 would not require translocations between facilities when periodic mixing was required.
Different from prokaryotes, targeting eukaryotic DNA requires nuclear translocation of the nucleases.
Quintana, A. et al. T cell activation requires mitochondrial translocation to the immunological synapse.
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