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However, such detailed analysis of reactions requires reaction data and information on the process conditions.
The Smoldyn algorithm used in Meredys requires reaction rates to be supplied to in order to determine an appropriate binding radius, σ [ 29].
Direct chemical conjugation to cells of a targeting entity, such as an antibody or a fragment derived from it is not straightforward and requires reaction conditions that may be toxic to cells and that could affect the properties of the entity attached.
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The other important aspect of ikigai is that it often is something external rather than internal ― it is about feeling alive, which requires reactions and responses from the outside world.
The overall rate equation allowing evaluation of conditions that provide required reaction rate could be expressed as:.
Aromatic carboxylic acids required reaction temperatures of 100 °C and 10% catalyst loading in order to increase the yields after 24 h reaction time.
A lack of equipment availability was experienced for the third stage, requiring reaction times in the hours range at well-defined flow conditions.
The current synthesis techniques based on co-precipitation and hydrothermal techniques require reaction time scales on the order of several hours making them difficult for scale-up.
Eukaryotic CPO (Elrod et al. 1997) forms the first oxygen requiring reaction within the heme biosynthetic pathway.
The sample preparation steps can be costly and time-consuming, and the required reaction conditions can degrade DNA [71].
Screening involves the use of a high-throughput assay to identify mutants which catalyse the required reaction.
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