Thus, by measuring the "average of averages" from data sets with limited numbers of fields (n = 3 - 10), a reasonable degree of reproducibility could be evaluated with fewer statistical comparisons and without requiring overly large amounts of beamtime.
Furthermore, in contrast to novel gene discovery, use of whole-exome sequencing to detect known pathogenic mutations does not require overly specialized data analyses or further in vitro experimental procedures to confirm their pathogenicity.
Three overall conclusions emerge from this example: a) indirect methods can provide realistic estimates of exposure only if reasonable assumptions are used; b) use of biomonitoring data can yield precise exposure estimates because it does not require overly conservative assumptions; and c) it may identify situations in which not all potential sources of exposure were considered.
They say the tax is poorly designed and overly complicated, requiring too much paperwork and discouraging large increases in giving by threatening foundations with the higher tax if they subsequently reduce how much they give to charity.
They are not required to overly emote, still less charm us, but their very natural performances are eloquent precisely because of their introverted taciturnity.
Stokes had clear and sensible ideas about the cars required, not overly cheap but "small, comfortable, fairly sophisticated, and capable of doing a lot of miles to a gallon of petrol".
But I really don't want to get into the business of trying to deduce the number of acquisition regulations that can dance on the head of a pin, so I'm sticking to a very specific kind of topic: things that are more or less insider absurdities that should be recognizable — or at least debatable— for any defense watcher, not things that require huge, overly technical explanations.
Third, our use of a modified stepped wedge design is novel and ideally suited for cases like ours when an intervention is presumed to do more good than harm, it is logistically impractical to offer the intervention simultaneously to all participants, and study outcomes do not require an overly long follow-up.
