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Effective reform requires major changes in patient behavior.
A healthier, if sometimes adversarial, relationship also requires major changes by business leaders, starting with the Business Roundtable.
It requires major changes in strategic goals, people and processes.
The organ development after birth requires major changes in several biological systems to become physiologically efficient.
In the short term, however, it is unlikely that any solution that requires major changes to infrastructure or special roads will be possible because of Formula E's plans to host the races in major city centres.
LCA methods and tools, however, were not conceived to spur product design activities and decisions towards sustainable End-of-life (EoL) product conception, while Ecodesign requires major changes to be implemented.
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Customizable: It should be a generic solution for different applications and be extensible to meet the requirements of more complex pipelines without requiring major changes in the underlying architecture or design.
That would require major changes in the American economy.
Halting this progressive alienation will require major changes in outlook and policy on both sides of the Atlantic.
The latest change to N.C.A.A. testing will apply even tougher standards, Russell said, requiring major changes to college bats by the 2011 season.
However, most charities and campaigning groups are not set up to account for spending on a constituency basis, and this would require major changes on accounting processes.
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