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The technical requirements of these methods and the mutational spectra were compared and discussed with references to commonly used techniques.
The prior knowledge requirements of these methods often limit their realistic applicability.
However, for the volume of data that is typical for family studies, the computational requirements of these methods are still enormous, so they cannot be used during the model building stage, where numerous exploratory analyses are performed.
As long as you fulfill the general requirements of these methods, you can get a star rank, but make sure to do them extremely well to match the quality of your performance to the quantity of the requirements.
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The significant computational work and memory requirement of these methods makes a numerical simulation of three-dimensional space-fractional diffusion equations computationally prohibitively expensive.
In light of the increasing availability of thousands of sequenced human genomes and databases of human genome variation, the requirement of these methods to use a single human reference genome leads to inherent biases towards the arbitrarily chosen reference.
However, due to the computational requirements of these two methods, initiating a study that spans the stirred mill design space would take a lot of computational effort and time.
We also consider several practical aspects of module detection, such as the relative data requirements of the methods, parameter estimation, and the use of alternative similarity measures for clustering.
However, for large scale ShakeMap grids, computational requirements of the method are prohibitive.
The initial experiments were performed to decide the basic analytical requirements of the method.
This method was obtained relaxing some of the requirements of the method provided by the European seismic code (Eurocode 8, EC8).
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