As is stated on letters to appellants: "Although an out-of-country appeal may be less advantageous … than in country, article 8 [of the convention] does not require that the appellant have access to the best possible procedure, only access to a procedure that meets the essential requirements of effectiveness and fairness".
However, most of these agents are unable to satisfy the requirements of effectiveness, low toxicity and specificity.
Besides patient safety, when added to the requirements of timeliness, effectiveness, efficiency, equitableness and patient-centered care [ 19], physicians' workloads often increase and shortage of physician manpower emerges.
For that, we felt that real-time quantitative PCR (qPCR) met the requirements of cost-effectiveness and easy execution [ 13– 13].
In face of this reality, we found in qPCR technique the requirements of cost-effectiveness and easy execution for targeted diagnosis of monosomy 1p36, easily accessible for low-budget laboratories in developing countries [ 13– 13].
Thus, opportunistic screening lacks some important requirements for effectiveness, including eligibility parameters, quality assurance of the technical proceedings, follow-up of positive test results, and program evaluation [ 9].
According to Kulynych's historical review, consideration of public safety was the basis of the requirement for effectiveness: if an ineffective drug replaces one of proven value, people can be harmed.
We may again consider that the limitation of this approach may be in the cost of the usage and deployment of dedicated helper nodes, particularly considering that its physical proximity to a PU is an important requirement of the effectiveness of this approach.
The rest of the medicines can meet the requirements of "safety, necessity, effectiveness, and competitive price".
The main differences between these algorithms are digital or analog implementation, simplicity of the design, sensor requirements, convergence speed, range of effectiveness, as well as hardware costs.
Because CO is the primary determinate by which oxygen donation to the tissue is varied to match metabolic requirements, the effectiveness of a resuscitation therapy can be evaluated best by continuous monitoring of cardiac output.
