Therefore, we wanted to summarise the reasons for excluding those PRO studies and make the authors of PRO studies aware of some basic requirements for reporting of comparative PRO data to achieve higher acceptance in the scientific community.
Requirements for comparative clinical efficacy studies vary across the guidelines from different countries, with a general trend toward no specific requirement for demonstration of efficacy per se (Table 3) and rather greater focus on safety assessment.
This consideration leads to a second requirement for comparative meta-analyses of diagnostic studies: the meta-analytic methods should adjust for the use of imperfect reference standards.
In Germany, the requirement for comparative assessments may affect up to 25% of all PPPs and around 50% of all uses of PPPs.
Hence, there is a requirement for comparative study to address the relative performance of the above-mentioned cases and hence to arrive at a better and efficient flow configuration.
NHRI employed a B4 genotype vaccine strain and established the Vero cell bank in accordance with the relevant requirements of the FDA., Based on a comparative study of the vaccine strains,, research with regards to process optimization,, serum-free culture techniques for inactivated vaccines, quality control methods, and immunogenicity assays has been conducted.
Two experimental designs were carried out for the comparative evaluation of water requirements of seven strawberry cultivars (Fragaria × ananassa Duch).
In general, it can be stated that the nanoparticle analysis method has to be chosen according to the requirements of the case in question and the comparative studies between different nanomaterials is difficult.
We also performed a comparative examination of repair requirements of different dI containing substrates in vitro and the results indicated that there were overlapping activities of several repair pathways in processing of dI in DNA.
The available sequence information enables us to take a comparative genomics approach to study the genomic requirements of wall teichoic acid in S. aureus by comparing them to the genes involved in B. subtilis teichoic acid synthesis.
