Sentence examples for requirements of binding from inspiring English sources

The detailed analysis of the designed peptide interactions and comparison of those peptides with the known peptides indicate that our method is able to detect the requirements of binding surface; such as hydrophilicity, electrostatic compatibility, aromatic interactions, sulfur atom and its interactions.

However the requirement of binding to DNA introduces a restriction on the possible arrangement of the components such that the protein-protein binding may be weakened by this extra strain but the additional synergistic stability of the three way complex more than compensates for this effect (Table 5).

By association with Aha1, Hsp90α may bypass the requirement of binding TPR domain containing co-chaperones, since secreted Hsp90α contains a truncated C-terminal domain, which is required for TPR-binding.

We initiated a study of the requirements for binding of the AI to its protein effector LasR by synthesizing a library of analogs with the HSL moiety replaced with different amines and alcohols.

To further analyze the requirements for binding of WRKY28, pairwise mutations of the sequence around the core at -445 were scanned in an m1 background.

These studies have provided information concerning the structural requirements of substrate binding pockets of enzymes and evaluation of enzyme kinetics.

Using a quantitative structure retention relationship (QSRR) approach the affinity data were interpreted in terms of structural requirements of specific binding sites on biomacromolecules.

The diversity of natural antibodies is limited by the genetic mechanisms that engender diversity and the functional requirements of antigen binding.

Based on the results of our models, the dual requirements of Ste5 binding to the plasma membrane and phosphorylative activation of Ste11 to jointly induce MAPK signaling is crucial for allowing the system to exhibit both graded and ultrasensitive response profiles.

These features make it a promising tool to study the conformational requirements of peptide binding to mu-receptor.

Instead, the identification of the structural requirements of Gli1/DNA binding and of an interfering small molecule provides valuable insights to optimize the pharmacologic strategies of direct Gli1 targeting to prevent its interaction with DNA and the subsequent functional outputs.