The accurate online state estimation for some types of nonlinear singularly perturbed systems is challenging due to extensive computational requirements, ill-conditioned gains and/or convergence issues.
But "[t]oo often federal requirements are ill-conceived, ineffective, and/or duplicative," a coalition of major U.S. research universities declared earlier this year.
Little is known about kidney outcomes and dialytic requirements in critically ill patients infected with pandemic H1N1.
Before 2010, no study provided unequivocal evidence that a blood conservation system reduced transfusion requirements in critically ill patients [21, 23, 25].
Introduction: Albeit practical implementation remains a concern, indirect calorimetry (IC) is the first choice technique for estimating energy requirements in critically ill patients.
The opioid-sparing [ 11] effect of dexmedetomidine may reduce opioid requirements in critically ill patients.
Energy requirements of critically ill septic shock patients treated in the ICU are particularly difficult to determine.
Before 2010, no study provided unequivocal evidence that a blood conservation system reduced transfusion requirements in critically ill patients [ 21, 23, 25].
Together with our findings, this suggests that although patients may have stricter consenting requirements, the seriously ill who are looking for breakthroughs may be less strict.
A landmark study by Hébert and colleagues [ 9], the transfusion requirements in critically ill patients (TRICC) study, demonstrated that a restrictive strategy of red blood cell (RBC) transfusion was as effective as a liberal strategy.
The optimal protein requirement for critically ill patients has been stated as 1.5 2.0 g/kg [ 26].
