Sentence examples for requirement of differentiation from inspiring English sources

Is zinc depletion a hallmark of pluripotency, or is zinc increase a requirement of differentiation?

The subsequent decrease in Brk levels that occurred when keratinocytes continued to differentiate might occur as a requirement of the differentiation process in primary cells.

We find that loss of Cdh1 is a limiting requirement for differentiation of pluripotent cells, and that experimental suppression of Cdh1 activity rescues the BMP-imposed block to differentiation.

Downregulation of EGFR signaling appears to be a requirement of keratinocyte differentiation and the reduction in signaling could be enhanced by reduced Brk levels.

This pool of cells reacted on environmental requirements by initiation of differentiation in specialized cells to maintain a balanced tumor microenvironment, ensured sufficient oxygen and nutrient supply and finally counteracted metronomic therapy.

Thus, loss of BALL does not bypass the requirement of BAM for differentiation.

However, the requirement of a transitional differentiation process from the hepatocyte to the cholangiocyte lineage makes it less likely that viral hepatitis-associated ICC arises from the proliferating hepatocytes.

Both in vivo and in vitro studies have demonstrated critical involvement of Wnt signal activation in T-lineage development (Verbeek et al., 1995; Staal et al., 2001; Mulroy et al., 2002), particularly the requirement of TCF7 for differentiation, and the necessity of Wnt signaling at early DN stages (Weerkamp et al., 2006).

Additional requirements for elucidating AD mechanisms might require better control of differentiation itself.

Our data from studies on murine macrophage differentiation in vitro and in vivo suggest that the requirement of ROS in the differentiation of monocytes to M2 macrophages is a general phenomenon.

This requirement of FBS for cardiac differentiation has previously been demonstrated [42].