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One important feature of spectroelectrochemical methods is the requirement for small reagent volumes to minimize the time required for the cell and to reach equilibrium at a given applied potential.
Here the problem is the transparency requirement for small companies.
Since there is no longer a requirement for small companies to submit their accounts to independent audit, the difference in accounting costs will generally not be substantial.
I'm personally just hoping that I'm ahead of the curve in my strict requirement for "small and silent".
According to the LaMer model [18], separation of nucleation and crystal growth stages is the main requirement for small particle formation with narrow size distributions.
The validation of biological quality control procedures for RCPs is a mandatory requirement for small scale radiopharmaceutical preparations (SSRP) in order to maintain good radiopharmacy practice (GRPP).
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Thus the very same proteoliposomes could be used to demonstrate a strict requirement for small-headgroup lipids when the trans-SNARE complex levels were limited by the 5 nM Vam7p, while with ample Vam7p (5 µM) and hence high trans-SNARE levels, this requirement was partially bypassed.
The 3+3 design is the most common method for dose evaluation in phase 1 studies and has the advantages of ease of implementation and interpretation, together with the requirement for smaller numbers of patients (Le Tourneau et al, 2009; Liu et al, 2013).
Coincidentally, Mr. Zion's death came at a time when the New York City Planning Commission is proposing to abolish requirements for small parks and plazas.
Various proposals for "growth" markets with special rules, or even a pan-European small-business stockmarket, are also much discussed in Brussels.Second markets with easier listing requirements for small and middling firms have a chequered history.
With the Internet providing more opportunities for swindles and the new federal JOBS act possibly waiving some regulatory requirements for small businesses seeking investors, the potential for even more fraud looms.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com