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This was achieved using Opal OP to wrap the DOCK application as a grid service and PERL for data manipulation purposes, alleviating the requirement for extensive knowledge of grid infrastructure.
This approach also does away with data retrieval and integration complexities arising from heterogeneously derived information attached to a single chemical entity in certain databases, manifested in the requirement for extensive involvement of a human expert to identify a set of descriptors suitable for a particular comparison.
This points to a requirement for extensive scientific innovation and DRR collaboration that reduces uncertainty, for better modeling, early warning, and more cost-effective approaches to hydrological and meteorological risks, both with respect to climate change and with respect to the translation of science and technology into actions.
And for stability and functionality at the cell surface there are requirements for hetero- and homo-multimerization [21], as well as a requirement for extensive N-linked glycosylation [14].
Given the requirement for extensive homologous recombination, this is plausible.
A microwell-plate-based approach, however, is associated with a high consumption of reagents and a requirement for extensive automation.
Similar(43)
The most recent substantive change came in 2006, when, in response to two separate murders of young women who'd visited Manhattan venues the night of their death, requirements for extensive security camera systems covering exits were added to the law.
One of the major advantages of antibody production in bacteria is the non-requirement for extensive testing for viruses and mammalian DNA, which is expensive and time consuming.
In terms of testing requirements, Helinor Johnston (Heriot-Watt University Edinburgh, UK) emphasized the necessity for extensive characterization of the nanomaterial in a given test medium, since physiochemical properties that drive toxicity may vary dramatically depending on the test system applied.
In this context, the requirement for relatively extensive safety evaluation and WF animal toxicity studies is disproportionate to the known risks and is discordant with the extensive data available.
As noted above, lower potency of NO3− as compared to NO2− is likely due to its reduced uptake by the organisms and requirement for more extensive metabolism to generate nitric oxide.
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