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Overall, depending on the taxonomic level chosen as a requirement for conservation significance, at least 18% of the new intergenic SCSs are conserved.
In a survey based at the British Museum, the number of polymer objects was so large (> 3000 objects) that only a representative part of the collection was examined and visual signs of degradation and requirement for conservation work were noted together with the surrounding environmental conditions [6].
Most of these residues were found to be under purifying selection, supporting a requirement for conservation of these residues to maintain function.
Consistent with a requirement for conservation in proteins involved in the processing of genetic information, fewer insertions and deletions were detected in such proteins.
Usually, core collections can be seen from two perspectives: from a taxonomist point of view, in which case rare alleles should be represented in any core collection; or from the point of view of a plant breeder, in which case the main requirement for conservation would be to maximize the representation of the genetic diversity of the species for practical purposes [ 1].
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With help of modern construction chemistry achievements, natural hydraulic limes can be modified to meet almost all kinds of requirements for conservation and restoration of cultural heritage.
In future versions of the software under development, a less strict SNP definition will be allowed in which requirements for conservation surrounding the SNP position are relaxed, allowing polymorphisms and indels in the region immediately surrounding the SNP position.
Satya et al. [ 20] built a software pipeline TOFI-beta for selecting target-specific probes that are unique relative to a database of non-targets, without requirements for conservation within a set of multiple targets, and illustrated its application in silico using two bacterial genomes.
As an example, the requirement for a specific core for the bHLH binding site, i.e., for a CAGCTG E-box for nerfin-1, deadpan and nervy, suggests that it is the TF itself that demands sequence conservation; however, the requirement for conserved flanking sequences suggests that additional specific factors may be involved.
Considering the high diversity found in forest trees [ 20- 25], the requirement for sequence conservation in regions surrounding a SNP may be too conservative.
The conservation of the C-terminus of the SROs suggests functional constraints and a subsequent requirement for the conservation of a particular structure.
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