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A very crucial requirement for application of an agent for delivery of both drugs and imaging probes to target a disease marker is the capability of the agent to cross the endothelial barrier and to allow for proper tissue penetration and distribution.
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§ 3.203 Requirements for application of this subpart F. § 3.204 Measure for market risk.
§ 217.203 Requirements for application of this subpart F. § 217.204 Measure for market risk.
The concept of differentiating 3 toxicological limits will clarify the requirements for application of clinical trials of new radiopharmaceuticals and allow much better planning of translational studies, thereby strengthening research efforts towards novel targeting agents for molecular imaging and molecular radiotherapy.
These necessary requirements for application of the proposed methodology are not sufficient to ensure that there are enough biological samples to obtain reliable predictions of regulation; statistical power depends on the extent of biological variability as well as the sample size.
We regard these features as the basic requirements for applications of membrane proteins in materials science.
High sensitivity is one of the most important requirements for applications of electrospray ionization mass spectrometry (ESI MS).
The sterilant fulfills the principal requirements for application to a population of stray canines.
A crucial requirement for the application of radiopharmaceuticals is the formation of a thermodynamically stable and kinetically inert complex of the radiometal with a suitable chelator, which is then linked to the targeting agent (Majkowska-Pilip & Bilewicz 2011).
A key requirement for the application of proteomics for the assessment of blastosol composition is the ability to quantify proteins in specimens derived from individual embryos.
One requirement for successful application of engineered scaffold is the development of new blood vessels, i.e., angiogenesis.
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CEO of Professional Science Editing for Scientists @ prosciediting.com