For the sake of simplicity, we consider the same value for all η j, j = 1, …, N, since the phenomenon of synchronization as doublet does not require variability in the cell sensitivity to synchronization.
PSP requires variability between samples, and in a typical proteomics set up, achieving more than 10000 protein identifications is uncommon.
Quantifying the association between characteristics and health outcomes requires variability in those characteristics to calculate a relative rate of harm or benefit arising.
Simulating an allele-specific RNA-seq experiment requires variability to differentiate alleles and a set of clearly defined transcriptional units from which to generate allele-specific reads.
Despite the possibility of requiring variability by composing heterotetramers with additional isoenzymes, it is also possible that paralogs are retained because GAPDH is also involved in the maintenance of specific subcellular structures, e.g. the bundling of microtubules [ 88].
Also, it requires variability in the age at the time of the event: if all events were to happen at exactly the same age (which is not the case in our study), then the method would fail.
In conclusion, Entropy should be used if a greater number of divergent regions are desired, while Weighted will find use when a small list of only the most significantly-divergent regions is required, and Variability behaves like Entropy when the sequences in the MSA are closely related, but behaves like Weighted in the remainder of cases.
To satisfy both the variability required by each customer and the variability required to satisfy different customers' needs, it may be necessary for such a company to use components from different suppliers, partly offering the same feature set.
The pharmaceutical industry requires narrow variability in the dissolution rate of hard gelatin capsules.
