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The time-dependent loss of Av1 specific activity at pH 9.5 required turnover of the complete system that was established by a series of changes in the pH 9.5 reaction conditions.
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If you've done things right, you can leave the portfolio alone for a long while, whereas the value style requires turnover.
Cell migration requires turnover of focal adhesions [26].
Formation of the isopeptide bond by PafA requires turnover of ATP to ADP [ 9].
These results also suggest that changes in membrane fatty acids in response to temperature require turnover and resynthesis of new lipid to achieve the temperature-adapted composition.
Nevertheless, generation of asymmetry must require turnover and redistribution of the polarity proteins at junctions; thus, it is unlikely that Dsh, Pk, and Dgo merely "lock" the transmembrane proteins in place.
The surprising lack of correlation between Chd1 occupancy and suppression of nucleosome turnover in the mutant suggests that Chd1 is not absolutely required for turnover at high transcription rates.
Patel, H. et al. The multi-FERM-domain-containing protein FrmA is required for turnover of paxillin-adhesion sites during cell migration of Dictyostelium.
Although the leader sequence of the precursor peptide is often required for turnover, the exact mode of recognition by the modifying enzymes remains unclear for many members of this class of natural products.
The Fall had seen off most of their punk-era peers as the 80s reached their midpoint, and Smith had realised keeping the group fresh and relevant required a turnover of musicians in the manner that a football team will "every so often, replace the centre forward".
Whether CES3 and/or CES1 are part of a redundant system required for turnover of the alveolar surfactant pool remains to be determined.
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