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There are schools, often in challenging urban areas, without the strong leadership required to make a difference and they need to be confronted.
Public-private partnerships will be required to tackle grand challenges, but we should not underestimate the 'social work' of organisation and institutional change required to make a difference, alongside the scientific work.
Investing in those who join the social work profession is very rewarding, and important if we are to make sure that the next generation has the expertise and professional confidence required to make a difference in the lives of the most vulnerable children in our society.
If the service can offer real value to the end user, and reach the kind of scale required to make a difference, there's hope — but that's a tall order.
"Perfection is not required to make a difference.
The effort required to make a difference in the world is massive.
Similar(52)
"Legislation to allow young people to stay in foster care until at least 21 is required to make a real difference".
There are several possible explanations for this apparent difference: some diagnoses, common among younger patients, such as polycystic renal disease and hereditary disorders, may be less amenable to prophylaxis; early diagnosis and prophylaxis may be rarer among younger patients; it is possible that long-term therapy is required to make a noticeable difference.
These results are supportive and encouraging that active learning in the context of G-quadruplex structures is a helpful tool, although clearly more than 10 further data points are required to make a substantial difference to the predictive power of the model.
Now the real work of putting in place the resources that are required to make a long lasting difference on the ground, can really start.
"They want to make a difference.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com